The moment the trend changes sides, and the three stages of a high-probability MSS.
The BOS confirms continuation. The market structure shift (MSS) marks a change in market structure, a clear break in price dynamics. It is the moment the market goes from a bullish sequence to a bearish one, or the other way around.

The MSS is the moment one of the highs or lows holding the trend together breaks, signalling a change of intent.
The significant high or low is the one that comes right before the local high or local low. That is why we wait for HL1 to break, not HL2, before calling the MSS.
This point is essential. If you struggle to identify the significant high or low, play with your timeframes until the picture is clear. If in doubt, move on.
A quality MSS is a complete institutional sequence, usually made of three elements:

As with the BOS, there are two schools of thought. For some, a close above the candle body is enough (MSS1). Others wait for a close above the wick (MSS2). Personally, I use the body; a close above the wick is my confirmation.
The BOS confirms the strength and continuation of a trend, while the MSS is the first warning of an imminent shift in institutional intent. Understand both breaks and you can anticipate the move instead of chasing it.

The rest is in the book
These pages are the first part of the book. The rest answers the two questions that matter: which pair to trade, and when to enter.